rOpenSci News Digest, October 2026 22 de octubre de 2026
Dear rOpenSci friends, it’s time for our monthly news roundup! You can read this post on our blog. Now let’s dive into the activity at and around rOpenSci! rOpenSci HQ Team update: thank you Mark Padgham! Mark Padgham is leaving rOpenSc... Continue reading: rOpenSci News Digest, October 2026
rOpenSci
Hybrid Machine Learning & Financial Econometrics: Building Volatility-Aware Dynamic Forecast Bands for Bitcoin 21 de octubre de 2026
When forecasting high-volatility financial assets like Bitcoin (BTC-USD), standard point-prediction models—whether classical ARIMA or deep neural networks—often fall short. A point estimate tells you where the model expects the price to go, but it completely ignores market regime shifts and changing risk levels. In this article, we construct ... Continue reading: Hybrid Machine Learning & […]
Selcuk Disci

Persistent neuronal stress signalling underlies Angelman syndrome phenotypes 21 de octubre de 2026
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11165-4Genetic and proteomic analyses in human neurons and mouse models of Angelman syndrome (AS) show that loss of the ubiquitin ligase UBE3A leads to an overabundance of asparagine synthetase, and that this is linked with many AS phenotypes.
Kwang-Soo Kim
WEE1 opposes APC/C<sup>CDH1</sup> activity to promote S phase entry 21 de octubre de 2026
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11188-xExperimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the toxic side effects of WEE1 inhibitors in cancer therapies.
Luc-Alban Vuillemenot

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